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It was sharper, almost sour

It's also common to lose some muscle mass along with fat while on these drugs, which can be problematic, Kessler writes

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Gastrointestinal side effects such as nausea, vomiting, or diarrhea can occasionally lead to dehydration, which may place additional stress on the kidneys if not managed appropriately

Semaglutide can raise hypoglycemia risk, especially alongside insulin or other glucose-lowering agents

Peptide therapy must be prescribed and supervised by a licensed physician